Increased Aerobic Fitness Is Associated with Cortical Thickness in Older Adults with Mild Vascular Cognitive Impairment

A recent article published in the Journal of Cognitive Enhancement reviews a randomized controlled trial with 71 older adults with sub-cortical ischemic vascular cognitive impairment (SIVCI).

At trial completion, compared with the control group, participants in the aerobic training group showed significantly improved aerobic fitness, increased change in cortical thickness, and change in the right superior temporal gyrus thickness. Maintenance of cortical thickness was independently and significantly associated with improved processing speed performance on the digit symbol substitution test (DSST) over the 6-month trial.  The study concluded, a 6-month aerobic training program may promote cognitive outcomes in older adults with mild SIVCI by improving aerobic fitness capacity and maintaining cortical thickness.